Article
Cleft lip and/or palate with monogenic autosomal recessive transmission in Pyrenees shepherd dogs.
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association - 1 Jan 2009
Kemp Cordula, Thiele Holger, Dankof Anja, Schmidt Gül, Lauster Carola, Fernahl Gabriele, Lauster Roland
Abstract excerpt
OBJECTIVE: To document the genetic background of Pyrenees shepherd dogs as it relates to the incidence of cleft lip and/or cleft palate, to describe the phenotype, and to determine possible candidate genes. DESIGN: Pedigree analysis was performed and blood samples were taken from five affected pups, their siblings, and parents. Seven candidate genes were selected and linkage analysis was performed. Further...
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