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Article

Second-pandemic strain of Vibrio cholerae from the Philadelphia cholera outbreak of 1849.

The New England journal of medicine - 23 Jan 2014

Devault Alison M, Golding G Brian, Waglechner Nicholas, Enk Jacob M, Kuch Melanie, Tien Joseph H, Shi Mang, Fisman David N, Dhody Anna N, Forrest Stephen, Bos Kirsten I, Earn David J D, Holmes Edward C, Poinar Hendrik N

Abstract excerpt

In the 19th century, there were several major cholera pandemics in the Indian subcontinent, Europe, and North America. The causes of these outbreaks and the genomic strain identities remain a mystery. We used targeted high-throughput sequencing to reconstruct the Vibrio cholerae genome from the p...

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PMID: 24401020
DOI: 10.1056/NEJMoa1308663

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24401020-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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