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Article

Independent regulation of reovirus membrane penetration and apoptosis by the mu1 phi domain.

PLoS pathogens - 1 Dec 2008

Danthi Pranav, Coffey Caroline M, Parker John S L, Abel Ty W, Dermody Terence S

Abstract excerpt

Apoptosis plays an important role in the pathogenesis of reovirus encephalitis. Reovirus outer-capsid protein mu1, which functions to penetrate host cell membranes during viral entry, is the primary regulator of apoptosis following reovirus infection. Ectopic expression of full-length and truncat...

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Identifiers

PMID: 19112493
DOI: 10.1371/journal.ppat.1000248
PMCID: PMC2600812

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19112493-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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