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Article

Essential functions of the Williams-Beuren syndrome-associated TFII-I genes in embryonic development.

Proceedings of the National Academy of Sciences of the United States of America - 6 Jan 2009

Enkhmandakh Badam, Makeyev Aleksandr V, Erdenechimeg Lkhamsuren, Ruddle Frank H, Chimge Nyam-Osor, Tussie-Luna Maria Isabel, Roy Ananda L, Bayarsaihan Dashzeveg

Abstract excerpt

GTF2I and GTF2IRD1 encoding the multifunctional transcription factors TFII-I and BEN are clustered at the 7q11.23 region hemizygously deleted in Williams-Beuren syndrome (WBS), a complex multisystemic neurodevelopmental disorder. Although the biochemical properties of TFII-I family transcription factors have been studied in depth, little is known about the specialized contributions of these factors in pathways...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19109438
DOI: 10.1073/pnas.0811531106
PMCID: PMC2629217

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Essential functions of the Williams-Beuren syndrome-associated TFII-I genes in embryonic development.PMID 19109438Read ↗

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