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Global Expression Profiling in Atopic Eczema Reveals Reciprocal Expression of Inflammatory and Lipid Genes

23 Dec 2008

Abstract excerpt

BACKGROUND: Atopic eczema (AE) is a common chronic inflammatory skin disorder. In order to dissect the genetic background several linkage and genetic association studies have been performed. Yet very little is known about specific genes involved in this complex skin disease, and the underlying molecular mechanisms are not fully understood. METHODOLOGY/FINDINGS: We used human DNA microarrays to identify a...

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PMID: 19107207
DOI: 10.1371/journal.pone.0004017

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