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Article

The p53 mRNA-Mdm2 interaction.

Cell cycle (Georgetown, Tex.) - 1 Jan 2009

Naski Nadia, Gajjar Madhavsai, Bourougaa Karima, Malbert-Colas Laurence, Fåhraeus Robin, Candeias Marco M

Abstract excerpt

The E3 ligase Mdm2 is a key regulator of p53 activity via a complex regulatory feedback system that involves all levels of expression control including transcription, mRNA translation and protein degradation. Best known is the effect of p53 on Mdm2 transcription and the capacity of Mdm2 to target p53 for degradation, but more recently the role of Mdm2 as a positive regulator of p53 activity has also started to...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19106616
DOI: 10.4161/cc.8.1.7326

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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