Article
Prostate cancer genomics: towards a new understanding.
Nature reviews. Genetics - 1 Feb 2009
Witte John S
Abstract excerpt
Recent genetics and genomics studies of prostate cancer have helped to clarify the genetic basis of this common but complex disease. Genome-wide studies have detected numerous variants associated with disease as well as common gene fusions and expression 'signatures' in prostate tumours. On the basis of these results, some advocate gene-based individualized screening for prostate cancer, although such testing...
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