Article
Stress-induced sodium excretion: a new intermediate phenotype to study the early genetic etiology of hypertension?
Hypertension (Dallas, Tex. : 1979) - 1 Feb 2009
Ge Dongliang, Su Shaoyong, Zhu Haidong, Dong Yanbin, Wang Xiaoling, Harshfield Gregory A, Treiber Frank A, Snieder Harold
Abstract excerpt
Impaired stress-induced pressure natriuresis, ie, an inadequate compensatory increase in urinary sodium excretion (U(Na)V) in response to a stress-induced blood pressure increase, may lead to the premature development of essential hypertension. To assess the heritability of baseline U(Na)V, stress U(Na)V, and the U(Na)V response to stress (Delta U(Na)V=stress U(Na)V- baseline U(Na)V), we studied 396 black and 494...
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