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Article

Two common single nucleotide polymorphisms in the gene encoding beta-carotene 15,15'-monoxygenase alter beta-carotene metabolism in female volunteers.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Apr 2009

Leung W C, Hessel S, Méplan C, Flint J, Oberhauser V, Tourniaire F, Hesketh J E, von Lintig J, Lietz G

Abstract excerpt

The key enzyme responsible for beta-carotene conversion into retinal is beta-carotene 15,15'-monoxygenase (BCMO1). Since it has been reported that the conversion of beta-carotene into vitamin A is highly variable in up to 45% of healthy individuals, we hypothesized that genetic polymorphisms in the BCMO1 gene could contribute to the occurrence of the poor converter phenotype. Here we describe the screening of the...

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PMID: 19103647
DOI: 10.1096/fj.08-121962

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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