Article
Phosphorus-31 magnetic resonance spectroscopy of skeletal muscle in maternally inherited diabetes and deafness A3243G mitochondrial mutation carriers.
Journal of magnetic resonance imaging : JMRI - 1 Jan 2009
van Elderen Saskia G C, Doornbos Joost, van Essen Einar H R, Lemkes Herman H P J, Maassen J Antonie, Smit Jan W A, de Roos Albert
Abstract excerpt
PURPOSE: To investigate high-energy phosphate metabolism in striated skeletal muscle of patients with Maternally Inherited Diabetes and Deafness (MIDD) syndrome. MATERIALS AND METHODS: In 11 patients with the MIDD mutation (six with diabetes mellitus [DM] and five non-DM) and eight healthy subjects, phosphocreatine (PCr) and inorganic phosphate (Pi) in the vastus medialis muscle was measured immediately after...
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