Article
The Arabidopsis BLAP75/Rmi1 homologue plays crucial roles in meiotic double-strand break repair.
PLoS genetics - 1 Dec 2008
Chelysheva Liudmila, Vezon Daniel, Belcram Katia, Gendrot Ghislaine, Grelon Mathilde
Abstract excerpt
In human cells and in Saccharomyces cerevisiae, BLAP75/Rmi1 acts together with BLM/Sgs1 and TopoIIIalpha/Top3 to maintain genome stability by limiting crossover (CO) formation in favour of NCO events, probably through the dissolution of double Holliday junction intermediates (dHJ). So far, very limited data is available on the involvement of these complexes in meiotic DNA repair. In this paper, we present the...
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