Article
The Arabidopsis MEI1 gene encodes a protein with five BRCT domains that is involved in meiosis-specific DNA repair events independent of SPO11-induced DSBs.
The Plant journal : for cell and molecular biology - 1 Aug 2003
Grelon Mathilde, Gendrot Ghislaine, Vezon Daniel, Pelletier Georges, Mathilde Grelon, Ghislaine Gendrot, Daniel Vezon, Georges Pelletier
Abstract excerpt
Arabidopsis thaliana MEI1 was first described as a gene involved in male meiosis, encoding a short protein showing homology with a human acrosin-trypsin inhibitor. We have isolated a new allele of mei1, and shown that in both mutants male and female meiosis are affected. In both reproductive pathways, meiosis proceeds while chromosomes become fragmented, resulting in aberrant meiotic products and in a strongly...
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