Article
Localization of O-glycans in MUC1 glycoproteins using electron-capture dissociation fragmentation mass spectrometry.
Glycobiology - 1 Apr 2009
Sihlbom Carina, van Dijk Härd Iris, Lidell Martin E, Noll Thomas, Hansson Gunnar C, Bäckström Malin
Abstract excerpt
MUC1 is a mucin glycoprotein containing multiple tandem repeats of 20 amino acids, with five serines and threonines that can be O-glycosylated. Here, we investigated the O-glycosylation site occupancy in MUC1 glycoproteins produced in two mutant CHO cell lines, Lec3.2.8.1 and ldlD. We found that...
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