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Article

In vivo and in vitro alterations in influenza A/H3N2 virus M2 and hemagglutinin genes: effect of passage in MDCK-SIAT1 cells and conventional MDCK cells.

Journal of clinical microbiology - 1 Feb 2009

Li Danjuan, Saito Reiko, Suzuki Yasushi, Sato Isamu, Zaraket Hassan, Dapat Clyde, Caperig-Dapat Isolde Ma, Suzuki Hiroshi

Abstract excerpt

No mutations were detected in the hemagglutinin gene of influenza A/H3N2 virus isolates from patients undergoing short-term amantadine treatment. However, genetic changes occurred after serial passage in either MDCK or MDCK-SIAT1 cells. Our results showed that only a few mutations were observed i...

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Source

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Identifiers

PMID: 19091815
DOI: 10.1128/JCM.00892-08
PMCID: PMC2643669

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19091815-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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