Article
RIM-BP3 is a manchette-associated protein essential for spermiogenesis.
Development (Cambridge, England) - 1 Feb 2009
Zhou Jing, Du Ya-Rui, Qin Wei-Hua, Hu Ye-Guang, Huang Yan-Nv, Bao Lan, Han Daishu, Mansouri Ahmed, Xu Guo-Liang
Abstract excerpt
During spermiogenesis, round spermatids are converted into motile sperm in mammals. The mechanisms responsible for sperm morphogenesis are poorly understood. We have characterized a novel protein, RIM-BP3, with a specialized function in spermatid development in mice. The RIM-BP3 protein is associated with the manchette, a transient microtubular structure believed to be important for morphogenesis during...
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