Article
"12 weeks' stopping rule" in the treatment of genotype 1 chronic hepatitis C: two prognostic categories under the same label?
Scandinavian journal of gastroenterology - 1 Aug 2008
Ladero José M, López-Alonso Gustavo, Devesa María J, Cuenca Francisca, Agreda Marta, Ortega Luis, Suárez Avelina, Díaz-Rubio Manuel
Abstract excerpt
OBJECTIVE: The current guidelines recommend maintenance of combined therapy for hepatitis C virus (HCV) genotype-1 chronic hepatitis when HCV-RNA is undetectable or < or = 2 log10 of baseline after 12 weeks of therapy. The aim of this study was to investigate whether the probability of obtaining sustained viral (SVR) response is similar when HCV-RNA is undetectable or is present at < or = 2 log10 level after 12...
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