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Article

Usefulness of viral kinetics for early prediction of a sustained virological response in HCV-1 non-responders re-treated with pegylated interferon and ribavirin.

Journal of hepatology - 1 Nov 2011

Deltenre Pierre, Corouge Marion, Canva Valérie, Castel Hélène, Wartel Faustine, Dharancy Sébastien, Louvet Alexandre, Lazrek Mouna, Moreno Christophe, Henrion Jean, Mathurin Philippe

Abstract excerpt

BACKGROUND & AIMS: Undetectable HCV RNA at 12 weeks is the stopping rule recommended in HCV patients in whom previous treatment has failed. Whether earlier virological criteria may be useful for deciding treatment discontinuation remains subject of debate. The aim of this study was to identify, in HCV-1 non-responders and relapsers to IFN or Peg-IFN and ribavirin, the earliest and most accurate predictor of...

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PMID: 21354445
DOI: 10.1016/j.jhep.2011.02.014

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