Article
Resistance to mucosal lysozyme compensates for the fitness deficit of peptidoglycan modifications by Streptococcus pneumoniae.
PLoS pathogens - 1 Dec 2008
Davis Kimberly M, Akinbi Henry T, Standish Alistair J, Weiser Jeffrey N
Abstract excerpt
The abundance of lysozyme on mucosal surfaces suggests that successful colonizers must be able to evade its antimicrobial effects. Lysozyme has a muramidase activity that hydrolyzes bacterial peptidoglycan and a non-muramidase activity attributable to its function as a cationic antimicrobial pept...
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