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Article

Epithelial cells within the human pancreas do not coexpress mesenchymal antigens: epithelial-mesenchymal transition is an artifact of cell culture.

Laboratory investigation; a journal of technical methods and pathology - 1 Feb 2009

Seeberger Karen L, Eshpeter Alana, Rajotte Ray V, Korbutt Gregory S

Abstract excerpt

Pancreatic mesenchymal stem cells (MSCs) may be derived from human beta-cells undergoing reversible epithelial-mesenchymal transition (EMT), suggesting that they could be a potential source of new beta-cells. In this study we sought to determine the origin of pancreatic MSCs in the nonendocrine pancreas. Double immunofluorescent (IF) staining and flow cytometry were used to assess the cell phenotype of...

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PMID: 19079324
DOI: 10.1038/labinvest.2008.122

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MSC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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