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NF-kappaB -94Ins/Del ATTG polymorphism modifies the association between dietary polyunsaturated fatty acids and HDL-cholesterol in two distinct populations.

Atherosclerosis - 1 Jun 2009

Fontaine-Bisson Bénédicte, Wolever Thomas M S, Connelly Philip W, Corey Paul N, El-Sohemy Ahmed

Abstract excerpt

We previously showed that polymorphisms in the tumor necrosis factor (TNF)-alpha gene, which is regulated by nuclear factor kappa B (NF-kappaB), modify the association between dietary polyunsaturated fatty acid (PUFA) intake and circulating HDL-cholesterol. Our objective was to determine whether a common polymorphism in the NFKB1 gene (-94Ins/Del ATTG) interacts with PUFA intake to affect HDL-cholesterol in two...

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Source

Identifiers

PMID: 19070859
DOI: 10.1016/j.atherosclerosis.2008.10.037

Genes

NFKB1
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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