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Single nucleotide polymorphism genotyping by mini-primer allele-specific amplification with universal reporter primers for identification of degraded DNA.

Analytical biochemistry - 1 Mar 2009

Asari Masaru, Watanabe Satoshi, Matsubara Kazuo, Shiono Hiroshi, Shimizu Keiko

Abstract excerpt

Single nucleotide polymorphism (SNP) is informative for human identification, and much shorter regions are targeted in analysis of biallelic SNP compared with highly polymorphic short tandem repeat (STR). Therefore, SNP genotyping is expected to be more sensitive than STR genotyping of degraded human DNA. To achieve simple, economical, and sensitive SNP genotyping for identification of degraded human DNA, we...

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PMID: 19070585
DOI: 10.1016/j.ab.2008.11.023

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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