Article
[Association between single nucleotide polymorphisms in the promoter of cyclooxygenase COX-2 gene and hereditary susceptibility to pancreatic cancer].
Zhonghua yi xue za zhi - 22 Jul 2008
Xu Dong-kui, Zhang Xue-mei, Zhao Ping, Cai Jian-chun, Zhao Dan, Tan Wen, Guo Yong-li, Lin Dong-xin
Abstract excerpt
OBJECTIVE: To evaluate the effects of -1290A > G, -1195G > A and -765G > C single nucleotide polymorphisms (SNPs) in the promoter of cyclooxygenase (COX)-2 gene on the risk of pathogenesis of pancreatic cancer. METHODS: Peripheral blood samples were collected from 283 patients with pancreatic cancer and 566 normal controls. Questionnaire survey was conducted to understand the demographic data and status of...
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