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Article

Comparison of nonsense-mediated mRNA decay efficiency in various murine tissues.

BMC genetics - 5 Dec 2008

Zetoune Almoutassem B, Fontanière Sandra, Magnin Delphine, Anczuków Olga, Buisson Monique, Zhang Chang X, Mazoyer Sylvie

Abstract excerpt

BACKGROUND: The Nonsense-Mediated mRNA Decay (NMD) pathway detects and degrades mRNAs containing premature termination codons, thereby preventing the accumulation of potentially detrimental truncated proteins. Intertissue variation in the efficiency of this mechanism has been suggested, which could have important implications for the understanding of genotype-phenotype correlations in various genetic disorders....

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Identifiers

PMID: 19061508
DOI: 10.1186/1471-2156-9-83
PMCID: PMC2607305

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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