Article
Heritability of P. falciparum and P. vivax malaria in a Karen population in Thailand.
PloS one - 1 Jan 2008
Phimpraphi Waraphon, Paul Richard, Witoonpanich Bhee, Turbpaiboon Chairat, Peerapittayamongkol Chayanon, Louicharoen Chalisa, Casademont Isabelle, Tungpradabkul Sumalee, Krudsood Srivicha, Kaewkunwal Jaranit, Sura Thanyachai, Looareesuwan Sornchai, Singhasivanon Pratap, Sakuntabhai Anavaj
Abstract excerpt
The majority of studies concerning malaria host genetics have focused on individual genes that confer protection against rather than susceptibility to malaria. Establishing the relative impact of genetic versus non-genetic factors on malaria infection and disease is essential to focus effort on key determinant factors. This relative contribution has rarely been evaluated for Plasmodium falciparum and almost never...
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