Article
Nuclear localization of the pre-mRNA associating protein THOC7 depends upon its direct interaction with Fms tyrosine kinase interacting protein (FMIP).
FEBS letters - 5 Jan 2009
El Bounkari Omar, Guria Anuja, Klebba-Faerber Sabine, Claussen Maike, Pieler Tomas, Griffiths John R, Whetton Anthony D, Koch Alexandra, Tamura Teruko
Abstract excerpt
THOC7 and Fms-interacting protein (FMIP) are members of the THO complex that associate with the mRNA export apparatus. FMIP is a nucleocytoplasmic shuttling protein with a nuclear localization signal (NLS), whereas THOC7 does not contain a typical NLS motif. We show here that THOC7 (50-137, amino...
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