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Article

Pharmacogenomics of tamoxifen and irinotecan therapies.

Clinics in laboratory medicine - 1 Dec 2008

Algeciras-Schimnich Alicia, O'Kane Dennis J, Snozek Christine L H

Abstract excerpt

Genetic variability in drugmetabolizing enzymes affects the toxicity and efficacy of many compounds, including the chemotherapeutic agents irinotecan and tamoxifen. The correlation of clinical response to polymorphisms in enzymes associated with metabolism of these two drugs has led to the recommendation that patients who receive them undergo genotyping analysis. Irinotecan toxicity in patients who have...

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Source

Identifiers

PMID: 19059062
DOI: 10.1016/j.cll.2008.05.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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