Article
CD96 interaction with CD155 via its first Ig-like domain is modulated by alternative splicing or mutations in distal Ig-like domains.
The Journal of biological chemistry - 23 Jan 2009
Meyer Dorothee, Seth Sebastian, Albrecht Jana, Maier Michael K, du Pasquier Louis, Ravens Inga, Dreyer Lutz, Burger Renate, Gramatzki Martin, Schwinzer Reinhard, Kremmer Elisabeth, Foerster Reinhold, Bernhardt Günter
Abstract excerpt
The adhesion receptor CD96 (TACTILE) is a transmembrane glycoprotein possessing three extracellular immunoglobulin-like domains. Among peripheral blood cells, CD96 is expressed on T cells as well as NK cells and a subpopulation of B cells. A possible function of this receptor in NK cell-mediated killing activities was suggested recently. Moreover, CD96 was described as a tumor marker for T-cell acute...
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