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Article

dhfr and dhps genotype and sulfadoxine-pyrimethamine treatment failure in children with falciparum malaria in the Democratic Republic of Congo.

Tropical medicine & international health : TM & IH - 1 Nov 2008

Alker Alisa P, Kazadi Walter M, Kutelemeni Albert K, Bloland Peter B, Tshefu Antoinette K, Meshnick Steven R

Abstract excerpt

OBJECTIVE: To determine the relationship between mutations in dhfr and dhps and SP treatment failure in Plasmodium falciparum malaria in the Democratic Republic of the Congo (DRC). METHODS: Therapeutic efficacy trial was conducted in Rutshuru, Eastern DRC, between June and September 2002, comparing sulfadoxine-pyrimethamine (SP), SP plus amodiaquine (AQSP) and artesunate plus SP (ASSP) regimens for treating...

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Identifiers

PMID: 19055622
DOI: 10.1111/j.1365-3156.2008.02150.x
PMCID: PMC2765712

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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