Article
Association between polymorphisms of FCRL3, a non-HLA gene, and Behçet's disease in a Chinese population with ophthalmic manifestations.
Molecular vision - 1 Jan 2008
Li Ke, Zhao Min, Hou Shengping, Du Liping, Kijlstra Aize, Yang Peizeng
Abstract excerpt
PURPOSE: Studies have shown a strong association of human leukocyte antigens-B51 (HLA-B51) with Behçet's disease (BD). However, little is known about the association of non-HLA genes with BD. The polymorphisms of the Fc receptor-like 3 gene (FCRL3), -169C/T, -110A/G, +358C/G, and +1381A/G, have been reported to be associated with several autoimmune diseases. This study was designed to determine whether the...
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