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Article

Field-caught permethrin-resistant Anopheles gambiae overexpress CYP6P3, a P450 that metabolises pyrethroids.

PLoS genetics - 1 Nov 2008

Müller Pie, Warr Emma, Stevenson Bradley J, Pignatelli Patricia M, Morgan John C, Steven Andrew, Yawson Alexander E, Mitchell Sara N, Ranson Hilary, Hemingway Janet, Paine Mark J I, Donnelly Martin J

Abstract excerpt

Insects exposed to pesticides undergo strong natural selection and have developed various adaptive mechanisms to survive. Resistance to pyrethroid insecticides in the malaria vector Anopheles gambiae is receiving increasing attention because it threatens the sustainability of malaria vector control programs in sub-Saharan Africa. An understanding of the molecular mechanisms conferring pyrethroid resistance gives...

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Identifiers

PMID: 19043575
DOI: 10.1371/journal.pgen.1000286
PMCID: PMC2583951

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Source receipt: pubmed, retrieved 7 Sept 2026.

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