Comparative analysis reveals concentration-dependent and site-specific detoxification gene expression patterns in pyrethroid-resistant Anopheles gambiae s.l. from Accra, Ghana.

Abstract excerpt

The role of detoxification enzymes in pyrethroid resistance intensity among malaria vectors remains a critical area of research. This study evaluated the role of detoxifying enzymes in driving resistance intensity in Anopheles mosquitoes from high insecticide resistance sites in Accra, Ghana. Larvae were collected from Tema, Abossey Okai, and Dansoman, and bioassays were performed on 3-5 days old adult females by...

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