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Article

Inflammatory events induced by brown spider venom and its recombinant dermonecrotic toxin: a pharmacological investigation.

Comparative biochemistry and physiology. Toxicology & pharmacology : CBP - 1 Apr 2009

Paludo Katia Sabrina, Biscaia Stellee Marcela Petris, Chaim Olga Meiri, Otuki Michel Fleith, Naliwaiko Katya, Dombrowski Patrícia Andréia, Franco Célia Regina Cavichiolo, Veiga Silvio Sanches

Abstract excerpt

Accidents involving Brown spider (Loxosceles sp.) venom produce a massive inflammatory response in injured region. This venom has a complex mixture of different toxins, and the dermonecrotic toxin is the major contributor to toxic effects. The ability of Loxosceles intermedia venom and a recombinant isoform of dermonecrotic toxin to induce edema and increase in vascular permeability was investigated. These toxins...

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Identifiers

PMID: 19041422
DOI: 10.1016/j.cbpc.2008.08.009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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