Article
Heterogeneous molecular background of the weak C, VS+, hr B-, Hr B- phenotype in black persons.
Transfusion - 1 Mar 2009
Pham Bach-Nga, Peyrard Thierry, Juszczak Genevieve, Dubeaux Isabelle, Gien Dominique, Blancher Antoine, Cartron Jean-Pierre, Rouger Philippe, Le Pennec Pierre-Yves
Abstract excerpt
BACKGROUND: The rare Hr(B)- phenotype is encoded by the (C)ce(s) haplotype when present at the homozygous state. This haplotype contains two altered genes: a hybrid RHD-CE-D(s) gene segregated with a ce(s) allele of RHCE (733C>G and 1006G>T substitutions in Exon 5 and Exon 7 respectively). The ai...
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