Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Interaction of Hb South Florida (codon 1; GTG-->ATG) and HbE, with beta-thalassemia (IVS1-1; G-->A): expression of different clinical phenotypes.

European journal of pediatrics - 1 Sept 2009

Tan Jin-Ai Mary Anne, Tan Kim-Lian, Omar Khairul Zaman, Chan Lee-Lee, Wee Yong-Chui, George Elizabeth

Abstract excerpt

INTRODUCTION: Interactions of different hemoglobin variants with thalassemia alleles can result in various clinical phenotypes. HbE-beta-thalassemia generally manifests with severe anemia where individuals exhibit beta-thalassemia major with regular blood transfusions or beta-thalassemia intermedia with periodic blood transfusions. This study presents a unique Malay family with three beta-globin gene defects-HbE,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to beta-Thalassemia
Share to Blood Transfusion

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hemoglobins, Abnormal

Share to Hepatomegaly

Share to Point Mutation

Share to RNA Splice Sites

Share to Splenomegaly

Source

Identifiers

PMID: 19034506
DOI: 10.1007/s00431-008-0877-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 9 closest

Interaction of Hb South Florida (codon 1; GTG-->ATG) and HbE, with beta-thalassemia (IVS1-1; G-->A): expression of different clinical phenotypes.PMID 19034506Read ↗

Interaction of hemoglobin E and several forms of alpha-thalassemia in Cambodian families.Semantic proximity Read ↗

Two beta-globin cluster-linked polymorphic loci in thalassemia patients of variable levels of fetal hemoglobin.Semantic proximity Read ↗

Hematological characterization of compound heterozygous hemoglobin Hope/E patients with and without alpha-thalassemia-1 SEA type deletion.Semantic proximity Read ↗

A large beta-thalassemia deletion in a family of Indonesian-Malay descent.Semantic proximity Read ↗

beta-thalassemia intermedia caused by compound heterozygosity for Hb Malay (beta codon 19 AAC-->AGC; asn-->Ser) and codons 41/42 (-CTTT) beta(0)-thalassemia mutation.Semantic proximity Read ↗

Coinheritance of High Oxygen Affinity Hb Helsinki [HBB: c.248A>T; β82(EF6)Lys→Met] with Hb H Disease.Semantic proximity Read ↗

Molecular mechanisms of thalassemia in southeast Asia.Semantic proximity Read ↗

Complex interactions of deltabeta hybrid haemoglobin (Hb Lepore-Hollandia) Hb E (beta(26G-->A)) and alpha+ thalassaemia in a Thai family.Semantic proximity Read ↗

Compound heterozygote states for Hb C/Hb Malay and Hb C/Hb E in pregnancy: a molecular and hematological analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.