Article
Complex interactions of deltabeta hybrid haemoglobin (Hb Lepore-Hollandia) Hb E (beta(26G-->A)) and alpha+ thalassaemia in a Thai family.
European journal of haematology - 1 Feb 2002
Viprakasit Vip, Pung-Amritt Parichat, Suwanthon Lerlugh, Clark Kevin, Tanphaichtr Vorvarn S
Abstract excerpt
Haemoglobin Lepore-Hollandia is an extremely rare condition in which a small deletion gives rise to a deltabeta hybrid, beta-like globin. There are two single reports of patients from South Pacific Islands and Bangladesh. We describe a family from central Thailand, in which this Hb Lepore-Hollandia interacts with a common beta globin variant (beta(E) resulting from the codon 26, G-->A mutation) and alpha(+)...
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