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Article

cDNA sequence and genomic structure of EV12B, a gene lying within an intron of the neurofibromatosis type 1 gene.

Genomics - 1 Mar 1991

Cawthon R M, Andersen L B, Buchberg A M, Xu G F, O'Connell P, Viskochil D, Weiss R B, Wallace M R, Marchuk D A, Culver M

Abstract excerpt

The gene responsible for neurofibromatosis type 1 (NF1), one of the more common inherited human disorders, was identified recently, and segments of it were cloned. Two translocation breakpoints that interrupt the NF1 gene in NF1 patients flank a 60-kb segment of DNA that contains the EV12A locus (previously reported as the EV12 locus), the human homolog of a mouse gene, Evi-2A, implicated in retrovirus-induced...

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PMID: 1903357
DOI: 10.1016/0888-7543(91)90410-g

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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