Article
Identification of neurofibromatosis 1 (NF1) homologous loci by direct sequencing, fluorescence in situ hybridization, and PCR amplification of somatic cell hybrids.
Genomics - 10 Dec 1995
Purandare S M, Huntsman Breidenbach H, Li Y, Zhu X L, Sawada S, Neil S M, Brothman A, White R, Cawthon R, Viskochil D
Abstract excerpt
Using fluorescence in situ hybridization (FISH), we have identified seven NF1-related loci, two separate loci on chromosome 2, at bands 2q21 and 2q33-q34, and one locus each on five other chromosomes at bands 14q11.2, 15q11.2, 18p11.2, 21q11.2-q21, and 22q11.2. Application of PCR using NF1 primer...
Topics
- Animals
- Base Composition
- Base Sequence
- Chromosome Mapping
- Chromosomes, Human, Pair 15
- Cloning, Molecular
- Cricetinae
- DNA Primers
- Humans
- Hybrid Cells
- In Situ Hybridization, Fluorescence