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Article

Sensitivity of phenotypic susceptibility analyses for nonthymidine nucleoside analogues conferred by K65R or M184V in mixtures with wild-type HIV-1.

The Journal of infectious diseases - 1 Jan 2009

Underwood Mark R, Ross Lisa L, Irlbeck David M, Gerondelis Peter, Rouse Elizabeth, St Clair Marty H, Trinh Lan, Parkin Neil, Lanier E Randall

Abstract excerpt

Thymidine-sparing triple-nucleoside regimens have exhibited poor virologic response despite apparent phenotypic susceptibility to 2 of 3 regimen components at early time points. Phenotypic resistance masking by wild-type virus may explain this discrepancy.Consistent with this notion were (1) the presence of low level nucleoside reverse-transcriptase inhibitor-resistant human immunodeficiency virus in subjects...

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Source

Identifiers

PMID: 19032103
DOI: 10.1086/595296

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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