Article
Pleomorphic adenoma of salivary glands does not appear to be a BRCA-1-dependent tumour in a Polish cohort.
Anticancer research - 1 Jan 2000
Lubiński Jakub, Tarnowska Czesława, Jaworowska Ewa, Byrski Tomasz, Jakubowska Anna, Górski Bogdan, Bień Stanisław, Sygut Jacek, Góźdź Stanisław, Siołek Monika, Sulikowski Mieczysław, Lubiński Jan
Abstract excerpt
BACKGROUND: The aim of the study was to examine whether pleomorphic adenoma of salivary glands can occur on the basis of constitutional BRCA-1 mutations. MATERIALS AND METHODS: Two hundred and sixty-eight patients affected by mixed tumour of salivary glands were examined for occurrence of three BRCA-1 mutations dominating in Poland. RESULTS: BRCA-1 mutation was detected in only one of the patients, a female...
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