Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[Molecular techniques lead to the first insights into the pathophysiology of salivary gland adenomas].

Verhandelingen - Koninklijke Academie voor Geneeskunde van Belgie - 1 Jan 2001

Kas K

Abstract excerpt

Pleomorphic adenomas are the most common type of salivary gland tumours. Activation of the PLAG1 gene on chromosome 8q12 is the most frequent mutation found in these tumours. This results from chromosomal translocations leading to promoter substitution between PLAG1, mainly expressed in fetal tis...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cells, Cultured
Share to DNA-Binding Proteins
Share to Gene Expression Regulation, Neoplastic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Insulin-Like Growth Factor II

Share to Models, Biological

Share to Mutation

Share to Salivary Gland Neoplasms

Share to Salivary Glands

Source

Identifiers

PMID: 11284386

Genes

PLAG1
IGF2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-11284386-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[Molecular techniques lead to the first insights into the pathophysiology of salivary gland adenomas].PMID 11284386Read ↗

PLAG1, the prototype of the PLAG gene family: Versatility in tumour development (Review)Semantic proximity Read ↗

Upregulation of Igf and Wnt signalling associated genes in pleomorphic adenomas of the salivary glands in PLAG1 transgenic miceSemantic proximity Read ↗

PLAG1 gene alterations in salivary gland pleomorphic adenoma and carcinoma ex-pleomorphic adenoma: a combined study using chromosome banding, in situ hybridization and immunocytochemistry.Semantic proximity Read ↗

Insights into the molecular alterations of PLAG1 and HMGA2 associated with malignant phenotype acquisition in pleomorphic adenoma.Semantic proximity Read ↗

Histologic localization of PLAG1 (pleomorphic adenoma gene 1) in pleomorphic adenoma of the salivary gland: cytogenetic evidence of common origin of phenotypically diverse cells.Semantic proximity Read ↗

Chromosome Translocations, Gene Fusions, and Their Molecular Consequences in Pleomorphic Salivary Gland AdenomasSemantic proximity Read ↗

Malignant transformation of salivary gland pleomorphic adenoma: proof of principleSemantic proximity Read ↗

[Salivary gland cancer: new therapeutic approaches].Semantic proximity Read ↗

Salivary gland development and diseaseSemantic proximity Read ↗

Molecular profile of a pleomorphic adenoma of the hard palateSemantic proximity Read ↗

New genetic findings in parotid gland pleomorphic adenomas.Semantic proximity Read ↗

Update in salivary gland cytopathology: Recent molecular advances and diagnostic applications.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.