Article
Analysis of the 206M polymorphic variant of the SLC26A6 gene encoding a Cl- oxalate transporter in patients with primary hyperparathyroidism.
European journal of endocrinology - 1 Feb 2009
Corbetta S, Eller-Vainicher C, Frigerio M, Valaperta R, Costa E, Vicentini L, Baccarelli A, Beck-Peccoz P, Spada A
Abstract excerpt
OBJECTIVE: Primary hyperparathyroidism (PHPT) is often complicated by kidney stones. Hypercalciuria and urine oxalate excretion are considered risk factors for urolithiasis in PHPT as well as in idiopathic stone-formers. Recently, the anion-exchanger SLC26A6 has been involved in the oxalate metabolism. DESIGN AND METHODS: We tested the hypothesis that the 206M polymorphic variant of SLC26A6 gene might contribute...
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