Article
A nucleotide-constrained single base extension method for improved detection of minority alleles in Plasmodium.
Molecular and biochemical parasitology - 1 Feb 2009
Farias Margaret E M, Jarvi Susan I
Abstract excerpt
In genetically mixed Plasmodium infections, minority alleles may have a significant role in drug resistance and other responses to selective pressures. Many available methods to detect single nucleotide polymorphisms representing minority alleles either are not sensitive enough to detect these ra...
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