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Article

Differentiation and transplantation of human embryonic stem cell-derived hepatocytes.

Gastroenterology - 1 Mar 2009

Basma Hesham, Soto-Gutiérrez Alejandro, Yannam Govardhana Rao, Liu Liping, Ito Ryotaro, Yamamoto Toshiyuki, Ellis Ewa, Carson Steven D, Sato Shintaro, Chen Yong, Muirhead David, Navarro-Alvarez Nalu, Wong Ronald J, Roy-Chowdhury Jayanta, Platt Jeffrey L, Mercer David F, Miller John D, Strom Stephen C, Kobayashi Naoya, Fox Ira J

Abstract excerpt

BACKGROUND & AIMS: The ability to obtain unlimited numbers of human hepatocytes would improve the development of cell-based therapies for liver diseases, facilitate the study of liver biology, and improve the early stages of drug discovery. Embryonic stem cells are pluripotent, potentially can differentiate into any cell type, and therefore could be developed as a source of human hepatocytes. METHODS: To generate...

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Identifiers

PMID: 19026649
DOI: 10.1053/j.gastro.2008.10.047
PMCID: PMC2732349

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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