Article
Functionally important movements in RecA molecules and filaments: studies involving mutation and environmental changes.
Acta crystallographica. Section D, Biological crystallography - 1 Nov 2008
Prabu J Rajan, Manjunath G P, Chandra Nagasuma R, Muniyappa K, Vijayan M
Abstract excerpt
The crystal structures of mutants of Mycobacterium smegmatis RecA (MsRecA) involving changes of Gln196 from glutamine to alanine, asparagine and glutamic acid, wild-type MsRecA and several of their nucleotide complexes have been determined using mostly low-temperature and partly room-temperature X-ray data. At both temperatures, nucleotide binding results in a movement of Gln196 towards the bound nucleotide in...
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