Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic analysis of the LexA repressor: isolation and characterization of LexA(Def) mutant proteins.

Molecular & general genetics : MGG - 1 Aug 1990

Oertel-Buchheit P, Lamerichs R M, Schnarr M, Granger-Schnarr M

Abstract excerpt

We report the isolation of LexA mutant proteins with impaired repressor function. These mutant proteins were obtained by transforming a LexA-deficient recA-lacZ indicator strain with a randomly mutagenized plasmid harbouring the lexA gene and subsequent selection on MacConkey-lactose indicator plates. A total of 24 different lexA(Def) missense mutations were identified. All except three mutant proteins are...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Bacterial Proteins
Share to Base Sequence

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Molecular Sequence Data

Share to Mutation

Share to Promoter Regions, Genetic

Share to Repressor Proteins

Source

Identifiers

PMID: 2259342
DOI: 10.1007/BF00315795

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic analysis of the LexA repressor: isolation and characterization of LexA(Def) mutant proteins.PMID 2259342Read ↗

recA operator mutations and their usefulness.Semantic proximity Read ↗

Mutant LexA proteins with an increased rate of in vivo cleavage.Semantic proximity Read ↗

A LexA mutant repressor with a relaxed interdomain linker.Semantic proximity Read ↗

Model of a LexA repressor dimer bound to recA operator.Semantic proximity Read ↗

Regulation and autoregulation by lexA protein.Semantic proximity Read ↗

Analysis of a DNA-binding motif of the Bacillus subtilis HrcA repressor protein.Semantic proximity Read ↗

One-step cloning system for isolation of bacterial lexA-like genes.Semantic proximity Read ↗

Intradomain LexA rotation is a prerequisite for DNA binding specificity.Semantic proximity Read ↗

Binding of the Bacillus subtilis LexA protein to the SOS operator.Semantic proximity Read ↗

Biochemical and biological function of Escherichia coli RecA protein: behavior of mutant RecA proteins.Semantic proximity Read ↗

A new regulatory DNA motif of the gamma subclass Proteobacteria: identification of the LexA protein binding site of the plant pathogen Xylella fastidiosa.Semantic proximity Read ↗

A brief consideration of the SOS inducing signal.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.