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Article

In vivo expansion of cells expressing acquired CSF3R mutations in patients with severe congenital neutropenia.

Blood - 15 Jan 2009

Germeshausen Manuela, Welte Karl, Ballmaier Matthias

Abstract excerpt

Severe congenital neutropenia (CN) is a rare bone marrow failure syndrome with a high incidence of acute leukemia. In previous studies, we could show that point mutations in the gene for the granulocyte colony-stimulating factor (G-CSF) receptor CSF3R are a highly predictive marker for leukemic development in CN patients. To find out at which stage of hematopoietic development these mutations emerge and how they...

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Source

Identifiers

PMID: 19020310
DOI: 10.1182/blood-2008-09-178087

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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