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Article

Adiponectin inhibits steatotic CD95/Fas up-regulation by hepatocytes: therapeutic implications for hepatitis C.

Journal of hepatology - 1 Jan 2009

Wedemeyer Inga, Bechmann Lars P, Odenthal Margarethe, Jochum Christoph, Marquitan Guido, Drebber Uta, Gerken Guido, Gieseler Robert K, Dienes Hans P, Canbay Ali

Abstract excerpt

BACKGROUND/AIMS: Steatosis may trigger hepatocytes to up-regulate CD95/Fas thereby increasing susceptibility to apoptosis, inflammation and fibrosis. We investigated this concept and potential roles of adiponectin and its receptors (AdipoR1; AdipoR2) in chronically HCV-infected patients. METHODS: In 98 HCV+ patients and 20 controls, sera were tested for HCV genotypes, FFAs, adiponectin and the M30 apoptosis...

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Identifiers

PMID: 19019483
DOI: 10.1016/j.jhep.2008.08.023

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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