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Article

Accuracy of combined protein gene product 9.5 and parafibromin markers for immunohistochemical diagnosis of parathyroid carcinoma.

The Journal of clinical endocrinology and metabolism - 1 Feb 2009

Howell Viive M, Gill Anthony, Clarkson Adele, Nelson Anne E, Dunne Robert, Delbridge Leigh W, Robinson Bruce G, Teh Bin T, Gimm Oliver, Marsh Deborah J

Abstract excerpt

CONTEXT: Parafibromin, encoded by HRPT2, is the first marker with significant benefit in the diagnosis of parathyroid carcinoma. However, because parafibromin is only involved in up to 70% of parathyroid carcinomas and loss of parafibromin immunoreactivity may not be observed in all cases of HRPT2 mutation, a complementary marker is needed. OBJECTIVE: We sought to determine the efficacy of increased expression of...

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Share to Carcinoma
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19017757
DOI: 10.1210/jc.2008-1740

Genes

UCHL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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