Article
Defining a molecular phenotype for benign and malignant parathyroid tumors.
Cancer - 15 Jan 2009
Fernandez-Ranvier Gustavo G, Khanafshar Elham, Tacha David, Wong Mariwil, Kebebew Electron, Duh Quan-Yang, Clark Orlo H
Abstract excerpt
BACKGROUND: It is frequently difficult to establish histologically whether a parathyroid tumor is a parathyroid carcinoma, parathyromatosis, or an atypical adenoma. The authors asked whether these tumors have a distinctive molecular profile, whether benign tumors could be distinguished from malignant tumors, and whether parathyromatosis is a low-grade parathyroid carcinoma or is benign tissue that can invade...
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