Article
Meta- and pooled analyses of the effect of glutathione S-transferase M1 and T1 deficiency on chronic obstructive pulmonary disease.
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease - 1 Dec 2008
Hu G, Yao W, Zhou Y, Hu J, Shi Z, Li B, Ran P
Abstract excerpt
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a complex polygenic disease in which gene-environment interactions are very important. A number of studies have investigated the genotypes of glutathione S-transferase M1 and T1 (GSTM1 and GSTT1) in relation to COPD susceptibility in different populations. However, the results of individual studies have been inconsistent. METHODS: To address the...
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